PhD or equivalent experience in an analytical/physchem/biophysics field. (Biopharm Analytical Scientist)
Experience of matrix and team membership in a Biotech or Biopharmaceutical environment.
Experience in leading customer-focused assay development especially electrophoretic assays e.g. capillary isoelectric focusing (c-IEF)
Good knowledge of CMC-relevant liabilities of Biopharmaceutical molecules.
Good understanding of ICH guidelines for analytical method development, analytical method qualification and validation. Knowledge and understanding of critical quality attributes is desireable..
Demonstrated innovator in Biopharmaceutical analytical sciences.
First-Class communications (oral, aural, written).
Experience in multi-project work packages.
GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery for strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.
Within the GSK Biopharmaceutical R&D Unit we are committed to the research, development and commercialisation of a highly novel pipeline of biopharmaceutical-based therapies to treat unmet medical needs. The Biopharmaceutical Product Development and supplies (BPDS) group are a new Department within GSK comprising approximately 60 Staff in the UK group. This department is dedicated to the identification of best-in-class, readily industrialised biopharmaceuticals, the development of cognate cell lines, processes and formulations, and the transfer of such into a CTM Manufacturing environment. BPDS operate as a single-team aligned with those of our key partners in Biopharm Medicine Discovery based within the same state-of-the-art Biopharm facilities at GSK-Stevenage.
We have a vacancy for an Analytical Scientist within our Analytical & Characterisation group. Your expertise in electrophoretic assay development such as cIEF using iCE280 and iCE3 technology will be key for this role to provide analytical data on therapeutic protein characterisation, stability studies and supporting early phase degradation studies. You will also be involved in physicochemical and biophysical characterisation, elucidating the primary degradation pathways of our therapeutic proteins and reporting of data from such studies. Basic understanding of formulation development is desirable.
Knowledge, Technical Skills and Expertise
With manager's direction, applies knowledge in area of specialization to assignments that involve multiple decision points.
Independently applies new techniques or approaches to the relevant work area.
Demonstrates good technical expertise and working familiarity with a number of methods, techniques and procedures including working to GMP standards.
Demonstrates ability to generate, collate, evaluate, and draw conclusions from data.
Has a good understanding of analytical chromatography and electrophoresis techniques and expertise in setting up, running and troubleshooting them. Shows experience and understanding of working with therapeutic proteins.
Demonstrates ability to organize and execute multiple tasks concurrently.
Independently and proactively executes a wide range of tasks within agreed timelines.
May be responsible for coordinating and/or executing portions of projects.
Identifies and analyzes problems on a reactive and proactive basis; recommends corrective actions to be taken.
Problems and issues are identified and next logical steps are defined and executed with minimal supervision. Anticipates and recognizes potential problems with equipment and initiate actions to troubleshoot.
Operates open access lab equipment with minimal supervision.
Leadership and Influence, and Development of Staff
Trains others in his or her area of technical expertise such as use of open access analytics.
May provide coaching and training to other staff if appropriate
Actively participates in departmental and cross-functional teams and provides input to decisions.
Actively participates or leads departmental or cross-functional teams and appropriately influences decision-making.
Begins to exhibit GSK Leadership Capabilities.
With assistance from manager, prepares oral and written summaries of results, conclusions, and recommendations for next steps
Effectively communicates oral and written summaries of results, conclusions and recommendations for next steps
Writes specific laboratory notebook reports with limited supervision.
Presents clearly and concisely to departmental forums.
Regularly discusses progress and activities with supervisor to assure appropriate follow-up. Keeps supervisor informed of progress and activities.
Networks with others as required to achieve primary project roles.
Begins to develop network through interactions with others outside of primary project roles.
Instinctive team player.
Application Closing Date: 07 July 2017
In your letter of application, please use the 'cover letter' to describe how you meet the competencies for this role as outlined above. Thank you for your interest in this opportunity. The information that you have provided in your cover letter and CV will be used to assess your application.
You may apply for this position online by selecting the Apply now button.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Salary: . Date posted: 05/04/2017